Department of Bioengineering,
School of Engineering,

The University of Tokyo


Hiroyuki Noji

Hiroyuki Noji



New Science and technology innovation by single-molecule and artificial cell reactor technologies



Purpose of Research

For over two decades, we have been studying the molecular mechanism of ATP synthase by single molecule technology. Through our research, we have been creating novel and innovative technologies such as femtoliter reactor array, that is currently utilized in digital bioassays such as ELISA, and ratiometric fluorescent ATP sensor proteins. Development of these new technologies is motivated more by our own curiosity rather than the need of the society. These technologies are widely used now and have been further developed by other researchers or companies.

Subjects of Reseach

Single-molecule biophysics of rotary molecular motors
Single-molecule digital bioassay with femtoliter reactor array
High-throughput Enzyme screening with artificial reactor array
Synthesis of autonomously self-replicating cell reactor


Enjoy Science and create new technology



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