Department of Bioengineering,
School of Engineering,

The University of Tokyo


Satoru Nagatoishi

Satoru Nagatoishi

Associate Professor

Chemical bioengineering

Advanced Biopharmaceutical Science using Biophysical Technologies



Purpose of Research

Developments and improvements of technology for the discovery and optimization of high-potency antibodies have greatly increased to find the specific and stable antibody with desired biological properties. Biophysical analyses of therapeutic antibody, particularly those of protein interaction and stability, are recognized as one of the critical procedures in the development of biopharmaceuticals, which would be assessed as an essential step to develop next generation antibodies. We study biophysical analyses of various antibody to propose new strategy for development of the next generation antibody.

Subjects of Reseach

Development of biophysical technology for antibody and small molecule drugs
Design of high-potential biopharmaceuticals using in silico methodology


We propose and design the innovative biopharmaceuticals.



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